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Open-source software may aid brain imaging to find disease treatments

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OSS

Researchers say the open-source software, called PySight, acts as a photon counting add-on for laser scanning microscopes. Because it can image deep into tissue, a laser-based technique known as multiphoton microscopy is often used to study the rapid activity of neurons, blood vessels and other cells at high resolution over time. The method uses laser pulses that excite fluorescent probes, eliciting the emission of photons, some of which are detected and used to form 2D and 3D images.

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  • Microscope add-on could be a game-changer for 2D, 3D brain imaging

    Researchers have developed an add-on for laser-scanning microscopes that can improve the quality of 2D and 3D imaging of the brain, according to a new study published in Optica.

    The add-on, called PySight, includes both hardware and open-source software. A laser-based imaging technique called multiphoton microscopy is often used to capture high-quality 2D and 3D images of neurons, blood vessels and other parts of a patient’s brain, the authors observed, but it can be difficult because the images must be taken quickly. This results in fewer photons being visible in the final image.

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As part of the research project on “The Interaction between Open Source Software and FRAND licensing in Standardisation”, a workshop was organised by the European Commission, Joint Research Centre (JRC) in collaboration with Directorate General Communications Networks, Content and Technology (CONNECT) to present and discuss the intermediate results to date. The workshop took place in Brussels on September 18, 2018. I presented a set of observations from the research on the case studies performed as part of the project that are outlined below. Other speakers where Catharina Maracke on the issue of legal compliance between Open Source and FRAND licenses, Bruce Perens on “Community Dynamics in Open Source”, and Andy Updegrove on “Dynamics in Standardisation”. You may ask what the relevance of this debate is for the wider Free and Open Source Software community. The obvious answer is that to distribute software “without restriction”, the user needs all the usage rights associated with the program. While most FOSS contributors assume that this is naturally the central motivation for anybody to contribute in the first place, there is a long history of attempts to maintain some sort of exclusive control over a piece of FOSS code, possibly using other rights than copyright. Read more

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