That is where my time with Linux Mint 17 "Qiana" MATE ended. I'm slightly disappointed to see the dependency issue crop up with M64Py, considering that the issue seems exclusive to Ubuntu and its derivatives; I'm just as disappointed to see Mupen64Plus not work even in its CLI form despite the absence of any indication of what the problem actually is. These issues of course may well be more the fault of those programs than of this distribution, but I can't deny that the experience was very slightly marred. Those are more personal opinions, though, and I still think that otherwise overall, Linux Mint 17 "Qiana" MATE continues to deliver a solid and reliable experience that is suitable for total newbies to Linux.
You can get it here.